Tuberculosis Testing | Health Answers (2024)

Jean Cherry, RN, MBA
Tuberculosis Testing | Health Answers (1)

What is tuberculosis?

Tuberculosis, also known as TB, is an infectious disease affecting the lungs and potentially the brain, kidney, and spine. It is caused by a bacteria called Mycobacterium tuberculosis. When a person with TB coughs, sneezes or speaks, the TB bacteria becomes airborne and can infect those nearby if they breathe in the bacteria. Common symptoms include a cough that lasts over three weeks, coughing up blood, and chest pain. TB can be active with symptoms or latent (inactive) in the body for years. If you have latent TB, the risk of it becoming active increases if the body's immune system is weakened from another disease, such as human immunodeficiency virus (HIV).

The number of people diagnosed with TB has been slowly decreasing by two percent each year over the past few decades. In the United States, 70% of people with TB were born outside of the country. As of 2018, the highest numbers of new TB cases were reported in India, China, Indonesia, Philippines, Pakistan, Nigeria, Bangladesh, and South Africa.

People are more likely to get TB from someone they live or work with rather than public areas. Active and latent TB can be cured by treatment with several medications given over a several weeks to months. A person is no longer contagious after two weeks of treatment. If TB is not treated appropriately, it can be fatal.

How is TB diagnosed?

A skin test or blood test can be used to diagnose TB. Your health care provider can help determine which test is right for you.

  • The Mantoux tuberculin skin test is performed in two visits to a health care provider. On the first visit, a small amount of tuberculin is injected underneath the skin of your forearm, making a small raised area. After 48-72 hours, your health care provider will check the skin for any palpable, raised, hardened area or swelling at the injection site. If the test is not read within 72 hours, it should be repeated. This is the preferred TB test for children younger than five years old.
  • There are two blood tests available for TB: the QuantiFERON®–TB Gold In-Tube test and the T-SPOT® TB test. For blood tests, you’ll only need one visit with your health care provider. During the visit, your provider will draw blood and then they’ll send to a laboratory for analysis. Blood tests are preferred for people who have trouble making two visits to their health care provider.

A negative skin or blood test result means there was no reaction to the test, and it is unlikely that you have active or latent TB. Testing positive for tuberculosis with any of these tests means you have TB, but the tests do not differentiate between the active and latent types of TB.

Your health care provider can order additional tests to determine which type of TB you have. These include chest X-rays or (computed tomography) CT scans to confirm any changes in the lungs from TB. A sputum test can also identify if TB is active when bacteria are present.

Where to get tuberculosis testing

Walgreens offers TB testing at select locations. Go to Walgreens.com or use the Walgreens app and select Find Care to find a site near you. TB Control Offices located in various cities, states, and territories and primary and urgent care clinics in your area may also offer TB testing.

Published on November 19, 2020

References:

Cornia, P, and BA Lipsky. 2020. Pertussis infection in adolescents and adults: Treatment and prevention. 02 18. Accessed 06 05, 2020. https://www.uptodate.com/contents/pertussis-infection-in-adolescents-and-adults-treatment-and-prevention?search=whooping%20cough%20vaccine&topicRef=5997&source=see_link.

Pertussis infection: Epidemiology, microbiology, and pathogenesis. 05 2020. Accessed 06 04, 2020. https://www.uptodate.com/contents/pertussis-infection-epidemiology-microbiology-and-pathogenesis?search=whooping%20cough%20adult&topicRef=8044&source=see_link.

Division of Tuberculosis Elimination. 2017. Center for Disease Control and Prevention: TB Control Offices. 02 17. Accessed 06 30, 2020. https://www.cdc.gov/tb/links/tboffices.htm.

Center for Disease Control and Prevention: Tuberculin Skin Testing. 05 04 2016. Accessed 06 29, 2020. https://www.cdc.gov/tb/publications/factsheets/testing/skintesting.htm.

Centers for Disease Control and Prevention: Questions and Answers About TB. 12 12 2012. Accessed 06 29, 2020. https://www.cdc.gov/tb/publications/faqs/qa_introduction.htm#tbprobleminus.

Centers for Disease Control and Prevention: Trends in Tuberculosis, 2018. 10 29 2019. Accessed 06 26, 2020. https://www.cdc.gov/tb/publications/factsheets/statistics/tbtrends.htm.

Drutz, JE. 2020. UpToDate: Patient education: Vaccines for infants and children age 0 to 6 years. 06 03. Accessed 06 09, 2020. https://www.uptodate.com/contents/vaccines-for-infants-and-children-age-0-to-6-years-beyond-the-basics?search=whooping%20cough%20vaccine%20side%20effects&topicRef=2844&source=see_link#H7.

Hibberd, PL. 2020. UpToDate: Patient education: Adult vaccines (Beyond the Basics). 01 30. Accessed 06 09, 2020. https://www.uptodate.com/contents/adult-vaccines-beyond-the-basics?search=whooping%20cough%20vaccine%20side%20effects&topicRef=1216&source=see_link.

Mayo Staff. 2019. Mayo Clinic: Tuberculosis. 01 30. Accessed 06 29, 2020. https://www.mayoclinic.org/diseases-conditions/tuberculosis/symptoms-causes/syc-20351250.

Nat Ctr for Immunization and Resp Diseases, Division of Bacterial Diseases. 2017. Pertussis (Whooping Cough) Fast Facts. 08 07. Accessed 06 05, 2020. https://www.cdc.gov/pertussis/fast-facts.html.

Whooping Cough Vaccination. 01 15 2019. Accessed 06 04, 2020. https://www.cdc.gov/pertussis/vaccines.html.

National Center for Immunization and Respiratory Diseases. 2020. 2020 Recommended Vaccinations for Infants and Children. 02 03. Accessed 06 05, 2020. https://www.cdc.gov/vaccines/schedules/easy-to-read/child-easyread.html.

National Institutes of Health. 2020. Medline Plus: Tuberculosis. 03 27. Accessed 06 29, 2020. https://medlineplus.gov/tuberculosis.html#cat_92.

National Institutes of Health's National Library of Medicine. 03 27 2020. Accessed 06 26, 2020. https://medlineplus.gov/tuberculosis.html#cat_93.

NIH: National Institute of Allergy and Infectious Diseases. 2016. Pertussis (Whooping Cough). 05 12. Accessed 06 04, 2020. https://www.niaid.nih.gov/diseases-conditions/pertussis-whooping-cough.

World Health Organization. 2017. "Communicating science-based messages on vaccines." Bulletin World Health Organ. 670-671. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689193/.

World Health Organization: Tuberculosis. 03 24 2020. Accessed 06 29, 2020. https://www.who.int/news-room/fact-sheets/detail/tuberculosis.

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Tuberculosis Testing | Health Answers (2024)

FAQs

Tuberculosis Testing | Health Answers? ›

These tests usually include a chest x-ray. They may also include a test of the sputum you cough up. Because TB germs may be found somewhere other than your lungs, your doctor or nurse may check your urine, take tissue samples, or do other tests.

What are the 4 TB screening questions? ›

Please answer the following questions:

Have you ever had a positive TB skin test? Have you ever had close contact with anyone who was sick with TB? Have you ever been vaccinated with BCG? * The significance of the travel exposure should be discussed with a health care provider and evaluated.

What are the results of tuberculosis test? ›

The test is "positive" if there is a bump of a certain size where the fluid was injected. This means you probably have TB germs in your body. Most people with a positive TB skin test have latent TB infection. To be sure, your doctor will examine you and give you a chest x-ray.

How do you test for tuberculosis? ›

TB blood tests (also called interferon-gamma release assays or IGRAs) use a blood sample to find out if you are infected with TB germs. The tests measure how your immune system reacts when a small amount of your blood is mixed with TB proteins.

What are the TB questions? ›

Have you ever had a positive TB skin test? Have you ever been vaccinated with BCG? Have you ever had close contact with persons known or suspected to have active TB disease?

What are the rules of TB testing? ›

Cows of any age or males over the age of 36 months, moving from one herd to another, through a mart or farm to farm, must be tested within the last 6 months and the herd that is moving them out must also be tested within the last 6 months. If not, these animals must be tested in the 30 days prior to or after movement.

What are the 4 pillars of TB? ›

The requirements for moving toward TB elimination have been integrated into the four strategic pillars of “Detect–Treat–Prevent–Build” (DTPB) [Table 2].

What does a positive TB test look like? ›

A positive TB skin test will look like a firm, red bump. Your provider will measure the size of the firmness of the bump (induration). Your provider considers your particular risk factors to determine the results of your test.

What happens if I test positive for TB? ›

A “positive” TB blood test result means you probably have TB germs in your body. Most people with a positive TB blood test have latent TB infection. To be sure, your doctor will examine you and do a chest x-ray. You may need other tests to see if you have latent TB infection or active TB disease.

What does TB stand for? ›

Tuberculosis (TB) is a serious illness that mainly affects the lungs. The germs that cause tuberculosis are a type of bacteria. Tuberculosis can spread when a person with the illness coughs, sneezes or sings. This can put tiny droplets with the germs into the air.

How to avoid tuberculosis? ›

Here are some tips for preventing TB infection:
  1. Avoid close contact with people who have active TB disease.
  2. Wash your hands often and cover your mouth when coughing or sneezing.
  3. Eat a nutritious diet and exercise regularly to keep your immune system strong.
Jun 28, 2023

How long does tuberculosis last? ›

Tuberculosis (TB) may last for several months, with treatment. The length of time it takes to cure the condition can vary. It may depend on whether the TB is latent or active. Tuberculosis (TB) is a bacterial disease that spreads through the air from person to person.

How do we confirm TB? ›

A diagnosis of latent TB infection is made if the person has a positive result from a TB blood test or TB skin test and a medical evaluation does not indicate TB disease. TB disease is diagnosed by medical history, physical examination, chest x-ray, and other laboratory tests, including culture.

What are 4 facts about tuberculosis? ›

Tuberculosis (TB) is an infectious disease that most often affects the lungs and is caused by a type of bacteria. It spreads through the air when infected people cough, sneeze or spit. Tuberculosis is preventable and curable. About a quarter of the global population is estimated to have been infected with TB bacteria.

How is TB transmitted? ›

Tuberculosis (TB) germs spread through the air from one person to another. TB germs can get into the air when someone with active TB disease coughs, speaks, or sings. People nearby may breathe in these germs and become infected. People with inactive TB, also called latent TB infection, cannot spread TB germs to others.

How long are TB tests good for? ›

to be repeated? If you have a negative skin test, you need a repeat test at least once every four years. If you have a documented positive skin test, you must have an initial chest X-ray. After that, you still need to be screened every four years.

What is the 4 symptom screening for TB? ›

Among adults and adolescents living with HIV, systematic screening for TB disease should be conducted using the WHO-recommended four symptom screen and those who report any one of the symptoms of current cough, fever, weight loss or night sweats may have TB and should be evaluated for TB and other diseases.

What is the 4S TB screening? ›

At ART centers, all PLHIV are screened for TB at every visit, using the 4-symptom (4S) complex which includes cough of any duration, fever, weight loss, and night sweats among adults. In children, the 4S complex includes current cough, fever, poor weight gain, and history of contact with a TB case.

What are the four tests used to diagnose tuberculosis? ›

Diagnosis
  • Medical history.
  • Physical examination.
  • TB blood tests or TB skin test.
  • Chest radiograph.
  • Bacteriologic examination (sputum smear microscopy, nucleic acid amplification testing, culture, and drug susceptibility testing)
May 20, 2024

What is the TB regimen 4? ›

The 4-month TB treatment regimen (high-dose daily rifapentine with moxifloxacin, isoniazid, and pyrazinamide) and 6-month RIPE (rifapentine, isoniazid, pyrazinamide, and ethambutol) regimen have unique considerations. The below table compares the recommended evaluation and testing considerations for the two regimens.

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